inverted optical microscope eclipse ts100  (Nikon)

Journal: Inorganic Chemistry

Article Title: Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models

doi: 10.1021/acs.inorgchem.4c04344

Figure Lengend Snippet: Representation of microscopic images illustrating the changes in the cellular morphology of A2780 ovarian cancer cells, 0 and 48 h after treatment with compounds 1 and 2 at concentrations of 0.5 × IC 50 , IC 50 , and 2 × IC 50 . The negative control was DMSO. The images were captured using a NIKON ECLIPSE TS100 microscope at 10× magnification.

Article Snippet: Possible morphological changes were evaluated at 0 and 48 h using an inverted optical microscope (NIKON ECLIPSE TS100) coupled with a Motcam 1SP camera, with a 10× objective lens.

Techniques: Negative Control, Microscopy

Journal: Inorganic Chemistry

Article Title: Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models

doi: 10.1021/acs.inorgchem.4c04344

Figure Lengend Snippet: Illustration of fluorescence microscopic images showing changes in the morphology of the A2780 ovarian cancer cells. Propidium iodide fluorescence after treatment with compounds 1 and 2 for 48 h at concentrations of 0.5 × IC 50 , IC 50 , and 2 × IC 50 . The negative control used was DMSO. The images were captured using a CELENA microscope at 10× magnification.

Article Snippet: Possible morphological changes were evaluated at 0 and 48 h using an inverted optical microscope (NIKON ECLIPSE TS100) coupled with a Motcam 1SP camera, with a 10× objective lens.

Techniques: Fluorescence, Negative Control, Microscopy

Journal: Inorganic Chemistry

Article Title: Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models

doi: 10.1021/acs.inorgchem.4c04344

Figure Lengend Snippet: Representation of changes in the morphology of A2780 ovarian cancer cells by fluorescence microscopic images with Green Plasma and DAPI markers. Data were obtained after treatment with compounds 1 and 2 for 48 h at concentrations of 0.5 × IC 50 , IC 50 , and 2 × IC 50 . The negative control was DMSO. The images were captured using a CELENA microscope at 10× magnification.

Article Snippet: Possible morphological changes were evaluated at 0 and 48 h using an inverted optical microscope (NIKON ECLIPSE TS100) coupled with a Motcam 1SP camera, with a 10× objective lens.

Techniques: Fluorescence, Clinical Proteomics, Negative Control, Microscopy

Journal: Inorganic Chemistry

Article Title: Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models

doi: 10.1021/acs.inorgchem.4c04344

Figure Lengend Snippet: (A) Effect of complex 1 , at different concentrations, on the cell morphology of spheroids of the A2780 tumor line, for 144 h. (B) Graph of spheroid diameter vs treatment time. (C) Fluorescence microscopy with DAPI and PI markers, after treatment for 144 h. The images were recorded using a CELENA microscope at 4x magnification. The negative control was DMSO.

Article Snippet: Possible morphological changes were evaluated at 0 and 48 h using an inverted optical microscope (NIKON ECLIPSE TS100) coupled with a Motcam 1SP camera, with a 10× objective lens.

Techniques: Fluorescence, Microscopy, Negative Control